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Helping CMT Patients Move Forward.

What is CMT?

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What We Do

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Charcot-Marie-Tooth Disease predominantly affects the nerves of the feet, legs, hands, and arms.

This causes nerve damage, leading to muscle weakness and numbness.

Charcot-Marie-Tooth disease can take away the ability to walk, run, and move freely—but it doesn’t have to. At Cure CMT, we provide direct funding for braces and surgery, giving people with CMT the support they need to stay mobile, independent, and active. We’re here to make an immediate difference—because when movement is possible, so is everything else.

We’re not waiting for a cure; we’re creating real solutions today so people can keep moving, thriving, and living to the fullest.

There is currently no cure for CMT

CMT affects 1 in 2,500 people in the United States and 3 million people worldwide.

CMT affects people of every race, gender, and ethnicity.

We’re on a mission to make an immediate impact on the lives of people living with CMT.

Braces: A Step In The Right Direction of Patient Mobility.

For many people with CMT, everyday movement can be a struggle due to muscle weakness, foot drop, and balance issues. Braces provide essential support, helping to stabilize the ankles, improve gait, improve balance, and reduce the risk of falls. The right braces can mean the difference between constant fatigue and confident mobility—allowing individuals to walk farther, stand longer, and stay active in their daily lives. By funding braces, we’re giving people with CMT the freedom to move with greater ease and independence.

Need a Brace? Considering Surgery? Apply for Assistance

Surgery: “My New Feet Look and Feel Like a Miracle.”

For some people with CMT, braces alone aren’t enough. Severe foot deformities, muscle imbalances, and joint instability can make walking painful and exhausting. Corrective surgery can realign the feet, restore function, and dramatically improve mobility. While the decision to undergo surgery is deeply personal, for many, it’s life-changing—reducing pain, increasing stability, and making every step feel like a miracle. By funding these procedures, we’re helping individuals with CMT take back their mobility and move through life with greater comfort and confidence.

We are looking to make an immediate difference NOW as we race for a cure for CMT. Braces and surgery have an immediate impact, but we are actively pursuing a cure for CMT, strategically investing in biotechs and companies that work toward this goal. We are making a difference for CMT patients now, and for the future.

Surgery Options

Providing Capital for a Cure 

We are investing in the future of CMT treatment—boldly funding the breakthroughs that will lead to the first-ever treatments and, ultimately, a cure.

With more than 100 known gene mutations causing CMT, researchers now have the knowledge to develop targeted therapies that can slow, stop, or even reverse the disease. Our mission is to accelerate that progress by funding cutting-edge biopharma, biotech, and academic research with real potential to change lives. We don’t just support research; we invest in it, ensuring the most promising CMT projects get the capital they need to move from the lab to clinical trials and, eventually, to patients.

Through strategic investments and partnerships with scientists, medical experts, industry leaders, and the CMT community, we are driving innovation and pushing research forward at an unprecedented pace. The time for waiting is over. CMT families need answers now, and we’re making sure they get them.

Since 2008, Cure CMT’s founder, Pat Livney, has played a pivotal role in identifying and funding groundbreaking research in CMT. His early efforts helped bring Sanofi-Genzyme into the fight against CMT.

This is more than hope. This is action. This is Cure CMT.

Today, the number of companies working on CMT research has grown exponentially. Our investment in them is growing each day but below is a representative sample.

Acurastem

Armatus Bio

Augustine Therapeutics

Cedars Sinai

Cypress Institute of Neurology & Genetics

DTx/Novartis

Ionis

Jackson Labs

Nanite

Nationwide Childrens Hospital

NIH

NMD Pharma

Oryzon

Ospedale San Raffaele

Psychogenics

ReviR Therapeutics

Samsara Therapeutics

Shift Pharma

University of Wisconsin

University of Wurzburg

Vanderbilt University

We also invest in academic research facilities that are making a profound impact on the cure for CMT.

Columbia University

Emory University

Loyola University

The Ohio State University

University of Illinois

University of Iowa

University of Miami

University of Missouri

University of Pennsylvania

University of Rochester

Our Impact

Lily’s Story

“I have CMT, but it doesn’t have me,” is my motto. I was four years old when I was diagnosed with Charcot-Marie-Tooth disease (CMT). Since then, it’s been a part of my life, but it has never defined me. CMT affects my peripheral nerves, making movement and sensation more difficult, but that hasn’t stopped me from pushing my limits and finding ways to thrive.

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New Therapy

A new clinical trial is offering hope for people with Charcot-Marie-Tooth (CMT) disease. Researchers tested a plasmid-based gene therapy designed to support nerve and muscle function. Unlike viral gene therapies, this treatment can be given multiple times without triggering an immune response—making it a promising option for chronic conditions like CMT.

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Your Donation Can Change Lives

For people living with Charcot-Marie-Tooth (CMT) disease, something as simple as walking can be a daily challenge. Braces and surgery can restore mobility and independence but they’re often out of reach due to high costs. Your donations make these life-changing treatments possible.

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