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I was four years old when I was diagnosed with Charcot-Marie-Tooth disease (CMT). Since then, it’s been a part of my life, but it has never defined me. CMT affects my peripheral nerves, making movement and sensation more difficult, but that hasn’t stopped me from pushing my limits and finding ways to thrive. When I was five years old, I had major foot surgery to correct the extreme curving caused by CMT. Learning to walk again was tough, but with…

A new clinical trial is offering hope for people with Charcot-Marie-Tooth (CMT) disease. Researchers tested a plasmid-based gene therapy designed to support nerve and muscle function. Unlike viral gene therapies, this treatment can be given multiple times without triggering an immune response—making it a promising option for chronic conditions like CMT. In a small Phase 1 trial in Seoul, South Korea, 12 participants with CMT type 1A received injections of the therapy over 104 days. The results? No serious side…

For people living with Charcot-Marie-Tooth (CMT) disease, something as simple as walking can be a daily challenge. Braces and surgery can restore mobility and independence but they’re often out of reach due to high costs. Your donations make these life-changing treatments possible. Why It Matters CMT is a progressive disease that weakens muscles and affects balance and mobility. Many patients need custom braces (AFOs) to walk safely or surgeries to correct painful foot deformities. These essential treatments aren’t always covered…